The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma

The secretion of interleukin-10 by both malignant and immune cells promotes the progression of lung tumors, hence negatively impacting on patient prognosis. As interleukin-10 mediates oncogenic effects through the PI3K/AKT signaling pathway, PI3K/AKT inhibitors might sensitize cancer cells to chemot...

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Detalles Bibliográficos
Autores principales: Sung, Wen-Wei, Lee, Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825731/
https://www.ncbi.nlm.nih.gov/pubmed/24244909
http://dx.doi.org/10.4161/onci.25854
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author Sung, Wen-Wei
Lee, Huei
author_facet Sung, Wen-Wei
Lee, Huei
author_sort Sung, Wen-Wei
collection PubMed
description The secretion of interleukin-10 by both malignant and immune cells promotes the progression of lung tumors, hence negatively impacting on patient prognosis. As interleukin-10 mediates oncogenic effects through the PI3K/AKT signaling pathway, PI3K/AKT inhibitors might sensitize cancer cells to chemotherapy, thus favoring tumor regression and improving disease outcome.
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spelling pubmed-38257312013-11-15 The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma Sung, Wen-Wei Lee, Huei Oncoimmunology Author's View The secretion of interleukin-10 by both malignant and immune cells promotes the progression of lung tumors, hence negatively impacting on patient prognosis. As interleukin-10 mediates oncogenic effects through the PI3K/AKT signaling pathway, PI3K/AKT inhibitors might sensitize cancer cells to chemotherapy, thus favoring tumor regression and improving disease outcome. Landes Bioscience 2013-09-01 2013-07-29 /pmc/articles/PMC3825731/ /pubmed/24244909 http://dx.doi.org/10.4161/onci.25854 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Sung, Wen-Wei
Lee, Huei
The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma
title The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma
title_full The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma
title_fullStr The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma
title_full_unstemmed The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma
title_short The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma
title_sort role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825731/
https://www.ncbi.nlm.nih.gov/pubmed/24244909
http://dx.doi.org/10.4161/onci.25854
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