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Virtual screening studies reveal linarin as a potential natural inhibitor targeting CDK4 in retinoblastoma

OBJECTIVE: To find out whether linarin can be used as a potential natural inhibitor to target CDK4 in retinoblastoma using virtual screening studies. MATERIALS AND METHODS: In this study, molecular modeling and protein structure optimization was performed for crystal structure of CDK4 (PDB id: 3G33)...

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Detalles Bibliográficos
Autores principales:	Sivashanmugam, Muthukumaran, Raghunath, Chandana, Vetrivel, Umashankar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826001/ https://www.ncbi.nlm.nih.gov/pubmed/24250202 http://dx.doi.org/10.4103/0976-500X.119711

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