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Finding the missing heritability in pediatric obesity: the contribution of genome-wide complex trait analysis
Known single-nucleotide polymorphisms (SNPs) explain <2% of the variation in body mass index (BMI) despite the evidence of >50% heritability from twin and family studies, a phenomenon termed ‘missing heritability'. Using DNA alone for unrelated individuals, a novel method (in a software p...
Autores principales: | Llewellyn, C H, Trzaskowski, M, Plomin, R, Wardle, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826033/ https://www.ncbi.nlm.nih.gov/pubmed/23528754 http://dx.doi.org/10.1038/ijo.2013.30 |
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