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A novel electrochemical method for efficient reduction of disulfide bonds in peptides and proteins prior to MS detection

A novel electrochemical (EC) method for fast and efficient reduction of the disulfide bonds in proteins and peptides is presented. The method does not use any chemical agents and is purely instrumental. To demonstrate the performance of the EC reactor cell online with electrospray mass spectrometry,...

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Detalles Bibliográficos
Autores principales:	Kraj, Agnieszka, Brouwer, Hendrik-Jan, Reinhoud, Nico, Chervet, Jean-Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826059/ https://www.ncbi.nlm.nih.gov/pubmed/24077854 http://dx.doi.org/10.1007/s00216-013-7374-3

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