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Regulation of MHC Class II-Peptide Complex Expression by Ubiquitination

MHC class II (MHC-II) molecules are present on antigen presenting cells (APCs) and these molecules function by binding antigenic peptides and presenting these peptides to antigen-specific CD4(+) T cells. APCs continuously generate and degrade MHC-II molecules, and ubiquitination of MHC-II has recent...

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Detalles Bibliográficos
Autores principales: Cho, Kyung-Jin, Roche, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826109/
https://www.ncbi.nlm.nih.gov/pubmed/24312092
http://dx.doi.org/10.3389/fimmu.2013.00369

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