Oxygenated Ylangene-Derived Sesquiterpenoids from the Soft Coral Lemnalia philippinensis

Chemical examination of a Taiwanese soft coral Lemnalia philippinensis led to the isolation of three oxygenated ylangene-derived sesquiterpenoids 1–3, including two new metabolites, philippinlins A and B (1 and 2). The structures of these compounds were elucidated on the basis of detailed spectrosco...

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Detalles Bibliográficos
Autores principales: Xio, Yun-Jie, Su, Jui-Hsin, Chen, Bo-Wei, Tseng, Yen-Ju, Wu, Yang-Chang, Sheu, Jyh-Horng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826132/
https://www.ncbi.nlm.nih.gov/pubmed/24084789
http://dx.doi.org/10.3390/md11103735
Descripción
Sumario:Chemical examination of a Taiwanese soft coral Lemnalia philippinensis led to the isolation of three oxygenated ylangene-derived sesquiterpenoids 1–3, including two new metabolites, philippinlins A and B (1 and 2). The structures of these compounds were elucidated on the basis of detailed spectroscopic data. Compound 1 was shown to exhibit cytotoxicity against HepG2, MDA-MB231 and A549 cancer cell lines.

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