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BRCA1 and BRCA2 Unclassified Variants and Missense Polymorphisms in Algerian Breast/Ovarian Cancer Families

Background: BRCA1 and BRCA2 germline mutations predispose heterozygous carriers to hereditary breast/ovarian cancer. However, unclassified variants (UVs) (variants with unknown clinical significance) and missense polymorphisms in BRCA1 and BRCA2 genes pose a problem in genetic counseling, as their i...

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Detalles Bibliográficos
Autores principales:	Cherbal, Farid, Salhi, Nadjet, Bakour, Rabah, Adane, Saida, Boualga, Kada, Maillet, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2012
Materias:	Other
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826381/ https://www.ncbi.nlm.nih.gov/pubmed/22684231 http://dx.doi.org/10.3233/DMA-2012-0893

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