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Assessing constraints on the path of regulatory sequence evolution

Structural and functional constraints are known to play a major role in restricting the path of evolution of protein activities. However, constraints acting on evolving transcriptional regulatory sequences, e.g. enhancers, are largely unknown. Recently, we elucidated how a novel expression pattern o...

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Detalles Bibliográficos
Autores principales: Glassford, William J., Rebeiz, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826499/
https://www.ncbi.nlm.nih.gov/pubmed/24218638
http://dx.doi.org/10.1098/rstb.2013.0026

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