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The role of red cell distribution width in the diagnosis of acute appendicitis: a retrospective case-controlled study
PURPOSE: The aim of this study was to seek whether red cell distribution width (RDW) has a role in the diagnosis of acute appendicitis. It was also aimed to show the relationship of RDW with leukocyte count and C-reactive protein (CRP) level. METHODS: This study was conducted via retrospective asses...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826504/ https://www.ncbi.nlm.nih.gov/pubmed/24216220 http://dx.doi.org/10.1186/1749-7922-8-46 |
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author | Narci, Huseyin Turk, Emin Karagulle, Erdal Togan, Turhan Karabulut, Keziban |
author_facet | Narci, Huseyin Turk, Emin Karagulle, Erdal Togan, Turhan Karabulut, Keziban |
author_sort | Narci, Huseyin |
collection | PubMed |
description | PURPOSE: The aim of this study was to seek whether red cell distribution width (RDW) has a role in the diagnosis of acute appendicitis. It was also aimed to show the relationship of RDW with leukocyte count and C-reactive protein (CRP) level. METHODS: This study was conducted via retrospective assessment of the hospital records of the adult patients who were operated for acute appendicitis between January 2010 and February 2013 and had a pathology report that confirmed the diagnosis of acute appendicitis. The patients in the control group were selected from healthy adults of similar age who applied to check-up clinic. Age, gender, leukocyte count, CRP, and RDW values were recorded. This study is a case controlled retrospective clinical study. RESULTS: A total of 590 patients in the acute appendicitis group and 121 patients in the control group were included, making up a total of 711 subjects. The mean RDW levels were 15.4 ± 1.5% in the acute appendicitis group, while 15.9 ± 1.4% in the control group. CRP, leukocyte count were significantly higher in the acute appendicitis group, and RDW level were significantly lower in the acute appendicitis group (p < 0.001, p < 0.001, p = 0.001, respectively). RDW, leukocyte count, and CRP had a sensitivity and specificity of 47% and 67%; 91% and 74%; and 97% and 41%, respectively in acute appendicitis. RDW was not correlated with CRP and leukocyte levels. However, we found a correlation between CRP and leukocyte levels. CONCLUSION: RDW level was lower in patients with acute appendicitis. The magnitude of difference in RDW seen between acute appendicitis and controls was so slight as to be of no utility in diagnostic testing. |
format | Online Article Text |
id | pubmed-3826504 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-38265042013-11-14 The role of red cell distribution width in the diagnosis of acute appendicitis: a retrospective case-controlled study Narci, Huseyin Turk, Emin Karagulle, Erdal Togan, Turhan Karabulut, Keziban World J Emerg Surg Research Article PURPOSE: The aim of this study was to seek whether red cell distribution width (RDW) has a role in the diagnosis of acute appendicitis. It was also aimed to show the relationship of RDW with leukocyte count and C-reactive protein (CRP) level. METHODS: This study was conducted via retrospective assessment of the hospital records of the adult patients who were operated for acute appendicitis between January 2010 and February 2013 and had a pathology report that confirmed the diagnosis of acute appendicitis. The patients in the control group were selected from healthy adults of similar age who applied to check-up clinic. Age, gender, leukocyte count, CRP, and RDW values were recorded. This study is a case controlled retrospective clinical study. RESULTS: A total of 590 patients in the acute appendicitis group and 121 patients in the control group were included, making up a total of 711 subjects. The mean RDW levels were 15.4 ± 1.5% in the acute appendicitis group, while 15.9 ± 1.4% in the control group. CRP, leukocyte count were significantly higher in the acute appendicitis group, and RDW level were significantly lower in the acute appendicitis group (p < 0.001, p < 0.001, p = 0.001, respectively). RDW, leukocyte count, and CRP had a sensitivity and specificity of 47% and 67%; 91% and 74%; and 97% and 41%, respectively in acute appendicitis. RDW was not correlated with CRP and leukocyte levels. However, we found a correlation between CRP and leukocyte levels. CONCLUSION: RDW level was lower in patients with acute appendicitis. The magnitude of difference in RDW seen between acute appendicitis and controls was so slight as to be of no utility in diagnostic testing. BioMed Central 2013-11-11 /pmc/articles/PMC3826504/ /pubmed/24216220 http://dx.doi.org/10.1186/1749-7922-8-46 Text en Copyright © 2013 Narci et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Narci, Huseyin Turk, Emin Karagulle, Erdal Togan, Turhan Karabulut, Keziban The role of red cell distribution width in the diagnosis of acute appendicitis: a retrospective case-controlled study |
title | The role of red cell distribution width in the diagnosis of acute appendicitis: a retrospective case-controlled study |
title_full | The role of red cell distribution width in the diagnosis of acute appendicitis: a retrospective case-controlled study |
title_fullStr | The role of red cell distribution width in the diagnosis of acute appendicitis: a retrospective case-controlled study |
title_full_unstemmed | The role of red cell distribution width in the diagnosis of acute appendicitis: a retrospective case-controlled study |
title_short | The role of red cell distribution width in the diagnosis of acute appendicitis: a retrospective case-controlled study |
title_sort | role of red cell distribution width in the diagnosis of acute appendicitis: a retrospective case-controlled study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826504/ https://www.ncbi.nlm.nih.gov/pubmed/24216220 http://dx.doi.org/10.1186/1749-7922-8-46 |
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