Cargando…
Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs – an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research
In recent years an increasing number of publications have emphasized the growing importance of hydrogen ion dynamics in modern cancer research, from etiopathogenesis and treatment. A proton [H(+)]-related mechanism underlying the initiation and progression of the neoplastic process has been recently...
Autores principales: | Harguindey, Salvador, Arranz, Jose Luis, Polo Orozco, Julian David, Rauch, Cyril, Fais, Stefano, Cardone, Rosa Angela, Reshkin, Stephan J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826530/ https://www.ncbi.nlm.nih.gov/pubmed/24195657 http://dx.doi.org/10.1186/1479-5876-11-282 |
Ejemplares similares
-
Effects of Hypoxia and Acidosis on Cardiac Electrophysiology and Hemodynamics. Is NHE-Inhibition by Cariporide Still Advantageous?
por: Salameh, Aida, et al.
Publicado: (2020) -
Towards an Integral Therapeutic Protocol for Breast Cancer Based upon the New H(+)-Centered Anticancer Paradigm of the Late Post-Warburg Era
por: Harguindey, Salvador, et al.
Publicado: (2020) -
Hydrogen Ion Dynamics as the Fundamental Link between Neurodegenerative Diseases and Cancer: Its Application to the Therapeutics of Neurodegenerative Diseases with Special Emphasis on Multiple Sclerosis
por: Harguindey, Salvador, et al.
Publicado: (2022) -
Increased NHE1 expression is targeted by specific inhibitor cariporide to sensitize resistant breast cancer cells to doxorubicin in vitro and in vivo
por: Chen, Qi, et al.
Publicado: (2019) -
Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question
por: Alfarouk, Khalid O., et al.
Publicado: (2014)