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Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells

Pancreatic islet β-cell insufficiency underlies pathogenesis of diabetes mellitus; thus, functional β-cell replacement from renewable sources is the focus of intensive worldwide effort. However, in vitro production of progeny that secrete insulin in response to physiological cues from primary human...

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Detalles Bibliográficos
Autores principales:	Lee, Jonghyeob, Sugiyama, Takuya, Liu, Yinghua, Wang, Jing, Gu, Xueying, Lei, Ji, Markmann, James F, Miyazaki, Satsuki, Miyazaki, Jun-ichi, Szot, Gregory L, Bottino, Rita, Kim, Seung K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2013
Materias:	Developmental Biology and Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826580/ https://www.ncbi.nlm.nih.gov/pubmed/24252877 http://dx.doi.org/10.7554/eLife.00940

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