Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity

Immediate-type drug hypersensitivity is an increasingly significant clinical issue; however, the diagnosis is frequently hindered due to lack of safe and precise diagnostic tests. Flow cytometry-assisted basophil activation test is a safe in vitro diagnostic tool for assessing basophil activation up...

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Autores principales: Song, Woo-Jung, Chang, Yoon-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2013
Materias:
Educational & Teaching Material
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826605/
https://www.ncbi.nlm.nih.gov/pubmed/24260732
http://dx.doi.org/10.5415/apallergy.2013.3.4.266
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author Song, Woo-Jung
Chang, Yoon-Seok
author_facet Song, Woo-Jung
Chang, Yoon-Seok
author_sort Song, Woo-Jung
collection PubMed
description Immediate-type drug hypersensitivity is an increasingly significant clinical issue; however, the diagnosis is frequently hindered due to lack of safe and precise diagnostic tests. Flow cytometry-assisted basophil activation test is a safe in vitro diagnostic tool for assessing basophil activation upon allergen stimulation. In this review, we have summarized current literature on the diagnostic utilities, new indications, and methodological aspects of the basophil activation test for the diagnosis of drug hypersensitivity.
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spelling pubmed-38266052013-11-20 Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity Song, Woo-Jung Chang, Yoon-Seok Asia Pac Allergy Educational & Teaching Material Immediate-type drug hypersensitivity is an increasingly significant clinical issue; however, the diagnosis is frequently hindered due to lack of safe and precise diagnostic tests. Flow cytometry-assisted basophil activation test is a safe in vitro diagnostic tool for assessing basophil activation upon allergen stimulation. In this review, we have summarized current literature on the diagnostic utilities, new indications, and methodological aspects of the basophil activation test for the diagnosis of drug hypersensitivity. Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2013-10 2013-10-31 /pmc/articles/PMC3826605/ /pubmed/24260732 http://dx.doi.org/10.5415/apallergy.2013.3.4.266 Text en Copyright © 2013. Asia Pacific Association of Allergy, Asthma and Clinical Immunology. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Educational & Teaching Material
Song, Woo-Jung
Chang, Yoon-Seok
Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity
title Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity
title_full Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity
title_fullStr Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity
title_full_unstemmed Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity
title_short Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity
title_sort recent applications of basophil activation tests in the diagnosis of drug hypersensitivity
topic Educational & Teaching Material
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826605/
https://www.ncbi.nlm.nih.gov/pubmed/24260732
http://dx.doi.org/10.5415/apallergy.2013.3.4.266
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AT changyoonseok recentapplicationsofbasophilactivationtestsinthediagnosisofdrughypersensitivity

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