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CYP1A2 polymorphism and theophylline clearance in Korean non-smoking asthmatics

BACKGROUND: Theophylline is mainly metabolized by cytochrome P450 (CYP) 1A2 and CYP2E1 which show inter-individual variations. However, the underlying mechanism remains unknown in humans. We investigated the relationship between differences in theophylline clearance and genetic polymorphisms in the...

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Detalles Bibliográficos
Autores principales:	Yim, Eun-Young, Kang, Hye-Ryun, Jung, Jae-Woo, Sohn, Seong-Wook, Cho, Sang-Heon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826610/ https://www.ncbi.nlm.nih.gov/pubmed/24260728 http://dx.doi.org/10.5415/apallergy.2013.3.4.231

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