Reactivation of latent HIV-1 in central memory CD4(+) T cells through TLR-1/2 stimulation

BACKGROUND: Toll-like receptors (TLRs) are crucial for recognition of pathogen-associated molecular patterns by cells of the innate immune system. TLRs are present and functional in CD4(+) T cells. Memory CD4(+) T cells, predominantly central memory cells (T(CM)), constitute the main reservoir of la...

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Detalles Bibliográficos
Autores principales: Novis, Camille L, Archin, Nancie M, Buzon, Maria J, Verdin, Eric, Round, June L, Lichterfeld, Mathias, Margolis, David M, Planelles, Vicente, Bosque, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826617/
https://www.ncbi.nlm.nih.gov/pubmed/24156240
http://dx.doi.org/10.1186/1742-4690-10-119

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