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Complement-Activating IgM Enhances the Humoral but Not the T Cell Immune Response in Mice
IgM antibodies specific for a certain antigen can enhance antibody responses when administered together with this antigen, a process believed to require complement activation by IgM. However, recent data show that a knock-in mouse strain, Cμ13, which only produces IgM unable to activate complement,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826713/ https://www.ncbi.nlm.nih.gov/pubmed/24250831 http://dx.doi.org/10.1371/journal.pone.0081299 |