The Role for Dickkopf-Homolog-1 in the Pathogenesis of Crohn’s Disease-Associated Fistulae

BACKGROUND: One of the most challenging conditions in Crohn’s disease (CD) patients is the treatment of perianal fistulae. We have recently shown that epithelial-to-mesenchymal transition (EMT) plays a crucial role during CD-fistulae development. Dickkopf-homolog 1 (DKK-1) is known to play a key rol...

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Detalles Bibliográficos
Autores principales: Frei, Sandra Michaela, Hemsley, Colette, Pesch, Theresa, Lang, Silvia, Weber, Achim, Jehle, Ekkehard, Rühl, Anne, Fried, Michael, Rogler, Gerhard, Scharl, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826763/
https://www.ncbi.nlm.nih.gov/pubmed/24250816
http://dx.doi.org/10.1371/journal.pone.0078882

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