Nrf2 deletion causes “benign” simple steatosis to develop into nonalcoholic steatohepatitis in mice fed a high-fat diet

BACKGROUND: Nonalcoholic fatty liver disease begins with the aberrant accumulation of triglyceride in the liver. Its spectrum includes the earliest stage of hepatic simple steatosis (SS), nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma. Generally, hepatic SS is often sel...

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Detalles Bibliográficos
Autores principales: Wang, Chunhua, Cui, Yizhe, Li, Chunyan, Zhang, Yanhua, Xu, Shang, Li, Xiaochong, Li, Hong, Zhang, Xiuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826845/
https://www.ncbi.nlm.nih.gov/pubmed/24188280
http://dx.doi.org/10.1186/1476-511X-12-165

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