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Genetic diversity of the highly variable V1 region interferes with Human Immunodeficiency Virus type 1 envelope functionality

BACKGROUND: The HIV envelope (Env) promotes viral entry in the host cell. During this process, Env undergoes several conformational changes to ensure its function. At the same time, the gp120 component of Env is the protein of the virus presenting the largest genetic diversity. Understanding how the...

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Detalles Bibliográficos
Autores principales: Hamoudi, Meriem, Simon-Loriere, Etienne, Gasser, Romain, Negroni, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826872/
https://www.ncbi.nlm.nih.gov/pubmed/24156625
http://dx.doi.org/10.1186/1742-4690-10-114