The perivascular niche regulates breast tumor dormancy

In a significant fraction of breast cancer patients, distant metastases emerge after years or even decades of latency. How disseminated tumor cells (DTCs) are kept dormant, and what ‘wakes them up’, are fundamental problems in tumor biology. To address these questions, we utilized metastasis assays...

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Detalles Bibliográficos
Autores principales: Ghajar, Cyrus M., Peinado, Héctor, Mori, Hidetoshi, Matei, Irina R., Evason, Kimberley J., Brazier, Hélène, Almeida, Dena, Koller, Antonius, Hajjar, Katherine A., Stainier, Didier Y.R., Chen, Emily I., Lyden, David, Bissell, Mina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826912/
https://www.ncbi.nlm.nih.gov/pubmed/23728425
http://dx.doi.org/10.1038/ncb2767

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