Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis

Lis1, Nudel/NudE, and dynactin are regulators of cytoplasmic dynein, a minus end–directed, microtubule (MT)-based motor required for proper spindle assembly and orientation. In vitro studies have shown that dynactin promotes processive movement of dynein on MTs, whereas Lis1 causes dynein to enter a...

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Detalles Bibliográficos
Autores principales: Wang, Shusheng, Ketcham, Stephanie A., Schön, Arne, Goodman, Benjamin, Wang, Yueju, Yates, John, Freire, Ernesto, Schroer, Trina A., Zheng, Yixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826990/
https://www.ncbi.nlm.nih.gov/pubmed/24025714
http://dx.doi.org/10.1091/mbc.E13-05-0283

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