A deubiquitinase negatively regulates retro-translocation of nonubiquitinated substrates

Endoplasmic reticulum (ER) membrane–bound E3 ubiquitin ligases promote ER-associated degradation (ERAD) by ubiquitinating a retro-translocated substrate that reaches the cytosol from the ER, targeting it to the proteasome for destruction. Recent findings implicate ERAD-associated deubiquitinases (DU...

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Detalles Bibliográficos
Autores principales: Bernardi, Kaleena M., Williams, Jeffrey M., Inoue, Takamasa, Schultz, Aric, Tsai, Billy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826992/
https://www.ncbi.nlm.nih.gov/pubmed/24068323
http://dx.doi.org/10.1091/mbc.E13-06-0332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826992/
https://www.ncbi.nlm.nih.gov/pubmed/24068323
http://dx.doi.org/10.1091/mbc.E13-06-0332

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