Cargando…

The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing

Brd2 is a member of the bromodomain extra terminal (BET) protein family, which consists of four chromatin-interacting proteins that regulate gene expression. Each BET protein contains two N-terminal bromodomains, which recognize acetylated histones, and the C-terminal protein–protein interaction dom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hnilicová, Jarmila, Hozeifi, Samira, Stejskalová, Eva, Dušková, Eva, Poser, Ina, Humpolíčková, Jana, Hof, Martin, Staněk, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826993/ https://www.ncbi.nlm.nih.gov/pubmed/24048450 http://dx.doi.org/10.1091/mbc.E13-06-0303

Ejemplares similares

Histone Deacetylase Activity Modulates Alternative Splicing
por: Hnilicová, Jarmila, et al.
Publicado: (2011)

PUF60-activated exons uncover altered 3′ splice-site selection by germline missense mutations in a single RRM
por: Královičová, Jana, et al.
Publicado: (2018)

The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells
por: Huranová, Martina, et al.
Publicado: (2010)

The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains
por: Alekseyenko, Artyom A., et al.
Publicado: (2015)

Identification of alternative topological domains in chromatin
por: Filippova, Darya, et al.
Publicado: (2014)

Sudemycin E influences alternative splicing and changes chromatin modifications
por: Convertini, Paolo, et al.
Publicado: (2014)

Fibronectin containing alternatively spliced extra domain A interacts at the central and c-terminal domain of Toll-like receptor-4
por: Gupta, Shubhangi, et al.
Publicado: (2022)

HIV-1 Vpr N-terminal tagging affects alternative splicing of the viral genome
por: Baeyens, Ann, et al.
Publicado: (2016)

Recruitment of Brd3 and Brd4 to acetylated chromatin is essential for proinflammatory cytokine-induced matrix-degrading enzyme expression
por: Dai, Jin, et al.
Publicado: (2019)

Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing
por: Glaich, Ohad, et al.
Publicado: (2019)

BRD4 is a Histone Acetyltransferase that Evicts Nucleosomes from Chromatin
por: Devaiah, Ballachanda N., et al.
Publicado: (2016)

Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1
por: Tauber, Maria, et al.
Publicado: (2020)

The bromodomain protein BRD4 regulates splicing during heat shock
por: Hussong, Michelle, et al.
Publicado: (2017)

The C-terminal low-complexity domain involved in liquid–liquid phase separation is required for BRD4 function in vivo
por: Wang, Chenlu, et al.
Publicado: (2019)

The Bromodomain Protein Brd4 Insulates Chromatin from DNA Damage Signaling
por: Floyd, Scott R., et al.
Publicado: (2013)

tBRD-1 and tBRD-2 regulate expression of genes necessary for spermatid differentiation
por: Theofel, Ina, et al.
Publicado: (2017)

DNA Damage Induces Dynamic Associations of BRD4/P-TEFb With Chromatin and Modulates Gene Transcription in a BRD4-Dependent and -Independent Manner
por: Song, Yawei, et al.
Publicado: (2020)

BRD9-mediated chromatin remodeling suppresses osteoclastogenesis through negative feedback mechanism
por: Du, Jiahui, et al.
Publicado: (2023)

Alternative Splicing of the N-Terminal Cytosolic and Transmembrane Domains of P2X7 Controls Gating of the Ion Channel by ADP-Ribosylation
por: Schwarz, Nicole, et al.
Publicado: (2012)

Dynamic condensation of linker histone C-terminal domain regulates chromatin structure
por: Luque, Antoni, et al.
Publicado: (2014)

Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation
por: Ai, Nanping, et al.
Publicado: (2011)

A novel BRD4-NUT fusion in an undifferentiated sinonasal tumor highlights alternative splicing as a contributing oncogenic factor in NUT midline carcinoma
por: Stirnweiss, A, et al.
Publicado: (2015)

In Vivo Reporters for Visualizing Alternative Splicing of Hormonal Genes
por: Kashkan, Ivan, et al.
Publicado: (2020)

A dynamic alternative splicing program regulates gene expression during terminal erythropoiesis
por: Pimentel, Harold, et al.
Publicado: (2014)

p73 Alternative Splicing: Exploring a Biological Role for the C-Terminal Isoforms
por: Vikhreva, Polina, et al.
Publicado: (2018)

Predicting the Impact of Alternative Splicing on Plant MADS Domain Protein Function
por: Severing, Edouard I., et al.
Publicado: (2012)

Alternative Splicing of the RAGE Cytoplasmic Domain Regulates Cell Signaling and Function
por: Jules, Joel, et al.
Publicado: (2013)

Chromatin features of plant telomeric sequences at terminal vs. internal positions
por: Majerová, Eva, et al.
Publicado: (2014)

Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport
por: Eisenreichova, Andrea, et al.
Publicado: (2023)

CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention
por: Pugacheva, Elena M., et al.
Publicado: (2020)

SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization
por: Gurzau, Alexandra D., et al.
Publicado: (2021)

Inhibition of the precursor and mature forms of HIV-1 protease as a tool for drug evaluation
por: Humpolíčková, Jana, et al.
Publicado: (2018)

The C-terminal tail domain of metavinculin, vinculin’s splice variant, severs actin filaments
por: Janssen, Mandy E.W., et al.
Publicado: (2012)

Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer
por: Wang, Wenyu, et al.
Publicado: (2021)

FET fusion oncoproteins interact with BRD4 and SWI/SNF chromatin remodelling complex subtypes in sarcoma
por: Lindén, Malin, et al.
Publicado: (2022)

Glioblastoma Mesenchymal Transition and Invasion are Dependent on a NF-κB/BRD2 Chromatin Complex
por: Vadla, Raghavendra, et al.
Publicado: (2023)

Alternative Splice in Alternative Lice
por: Tovar-Corona, Jaime M., et al.
Publicado: (2015)

FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism
por: Shah, Sneha, et al.
Publicado: (2020)

Chromatin-Associated Protein Sugp2 Involved in mRNA Alternative Splicing During Mouse Spermatogenesis
por: Zhan, Junfeng, et al.
Publicado: (2021)

Preparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes
por: Hügle, Martin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_hior7of6eol3pnp8ej4dahhtbm