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Transgenic Mouse Model Harboring the Transcriptional Fusion Ccl20-Luciferase as a Novel Reporter of Pro-Inflammatory Response

The chemokine CCL20, the unique ligand of CCR6 functions as an attractant of immune cells. Expression of CCL20 is induced by Toll-like Receptor (TLR) signaling or proinflammatory cytokine stimulation. However CCL20 is also constitutively produced at specific epithelial sites of mucosa. This expressi...

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Detalles Bibliográficos
Autores principales: Crispo, Martina, Van Maele, Laurye, Tabareau, Julien, Cayet, Delphine, Errea, Agustina, Ferreira, Ana María, Rumbo, Martin, Sirard, Jean Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827052/
https://www.ncbi.nlm.nih.gov/pubmed/24265691
http://dx.doi.org/10.1371/journal.pone.0078447