SomatiCA: Identifying, Characterizing and Quantifying Somatic Copy Number Aberrations from Cancer Genome Sequencing Data

Whole genome sequencing of matched tumor-normal sample pairs is becoming routine in cancer research. However, analysis of somatic copy-number changes from sequencing data is still challenging because of insufficient sequencing coverage, unknown tumor sample purity and subclonal heterogeneity. Here w...

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Detalles Bibliográficos
Autores principales: Chen, Mengjie, Gunel, Murat, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827077/
https://www.ncbi.nlm.nih.gov/pubmed/24265680
http://dx.doi.org/10.1371/journal.pone.0078143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827077/
https://www.ncbi.nlm.nih.gov/pubmed/24265680
http://dx.doi.org/10.1371/journal.pone.0078143

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