Cargando…

Development of a Clinically-Precise Mouse Model of Rectal Cancer

Currently-used rodent tumor models, including transgenic tumor models, or subcutaneously growing tumors in mice, do not sufficiently represent clinical cancer. We report here development of methods to obtain a highly clinically-accurate rectal cancer model. This model was established by intrarectal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kishimoto, Hiroyuki, Momiyama, Masashi, Aki, Ryoichi, Kimura, Hiroaki, Suetsugu, Atsushi, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827128/ https://www.ncbi.nlm.nih.gov/pubmed/24265772 http://dx.doi.org/10.1371/journal.pone.0079453

Ejemplares similares

Precise navigation surgery of tumours in the lung in mouse models enabled by in situ fluorescence labelling with a killer-reporter adenovirus
por: Yano, Shuya, et al.
Publicado: (2015)

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models
por: Yano, Shuya, et al.
Publicado: (2015)

Real-Time Fluorescence Image-Guided Oncolytic Virotherapy for Precise Cancer Treatment
por: Yano, Shuya, et al.
Publicado: (2021)

Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models
por: Yano, Shuya, et al.
Publicado: (2016)

Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic Mouse Model
por: Yano, Shuya, et al.
Publicado: (2016)

Review: Precise sarcoma patient-derived orthotopic xenograft (PDOX) mouse models enable identification of novel effective combination therapies with the cyclin-dependent kinase inhibitor palbociclib: A strategy for clinical application
por: Higuchi, Takashi, et al.
Publicado: (2022)

Color-coding cancer and stromal cells with genetic reporters in a patient-derived orthotopic xenograft (PDOX) model of pancreatic cancer enhances fluorescence-guided surgery
por: Yano, Shuya, et al.
Publicado: (2015)

Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence
por: Yano, Shuya, et al.
Publicado: (2016)

The rare BRAF VK600-601E mutation as a possible indicator of poor prognosis in rectal carcinoma – a report of a case
por: Mori, Yoshiko, et al.
Publicado: (2015)

The disintegrin echistatin in combination with doxorubicin targets high-metastatic human osteosarcoma overexpressing α(v)β(3) integrin in chick embryo and nude mouse models
por: Tome, Yasunori, et al.
Publicado: (2016)

Selective methioninase-induced trap of cancer cells in S/G(2) phase visualized by FUCCI imaging confers chemosensitivity
por: Yano, Shuya, et al.
Publicado: (2014)

Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma
por: Yano, Shuya, et al.
Publicado: (2015)

Efficacy of a Cell-Cycle Decoying Killer Adenovirus on 3-D Gelfoam(®)-Histoculture and Tumor-Sphere Models of Chemo-Resistant Stomach Carcinomatosis Visualized by FUCCI Imaging
por: Yano, Shuya, et al.
Publicado: (2016)

Fluorescence-Guided Surgery in Combination with UVC Irradiation Cures Metastatic Human Pancreatic Cancer in Orthotopic Mouse Models
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Fluorescence-Guided Surgery and Fluorescence Laparoscopy for Gastrointestinal Cancers in Clinically-Relevant Mouse Models
por: Metildi, Cristina A., et al.
Publicado: (2013)

High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models
por: Kawaguchi, Kei, et al.
Publicado: (2016)

Disintegrin targeting of an α(v)β(3) integrin-over-expressing high-metastatic human osteosarcoma with echistatin inhibits cell proliferation, migration, invasion and adhesion in vitro
por: Tome, Yasunori, et al.
Publicado: (2016)

In Vivo Fluorescence Imaging Reveals the Promotion of Mammary Tumorigenesis by Mesenchymal Stromal Cells
por: Ke, Chien-Chih, et al.
Publicado: (2013)

Prone-position thoracoscopic resection of posterior mediastinal lymph node metastasis from rectal cancer
por: Shirakawa, Yasuhiro, et al.
Publicado: (2015)

The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model
por: Higuchi, Takashi, et al.
Publicado: (2019)

Metastatic Recurrence in a Pancreatic Cancer Patient Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Is Inhibited by Neoadjuvant Chemotherapy in Combination with Fluorescence-Guided Surgery with an Anti-CA 19-9-Conjugated Fluorophore
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Osimertinib regressed an EGFR-mutant lung-adenocarcinoma bone-metastasis mouse model and increased long-term survival
por: Higuchi, Takashi, et al.
Publicado: (2020)

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

FUCCI Real-Time Cell-Cycle Imaging as a Guide for Designing Improved Cancer Therapy: A Review of Innovative Strategies to Target Quiescent Chemo-Resistant Cancer Cells
por: Yano, Shuya, et al.
Publicado: (2020)

Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models
por: Hiroshima, Yukihiko, et al.
Publicado: (2015)

Chronic spinal cord injury functionally repaired by direct implantation of encapsulated hair-follicle-associated pluripotent (HAP) stem cells in a mouse model: Potential for clinical regenerative medicine
por: Obara, Koya, et al.
Publicado: (2022)

Development of a Cantilever-Type Electrostatic Energy Harvester and Its Charging Characteristics on a Highway Viaduct
por: Koga, Hideaki, et al.
Publicado: (2017)

Establishment of a Patient-Derived Orthotopic Xenograft (PDOX) Model of HER-2-Positive Cervical Cancer Expressing the Clinical Metastatic Pattern
por: Hiroshima, Yukihiko, et al.
Publicado: (2015)

Essential updates 2020/2021: Advancing precision medicine for comprehensive rectal cancer treatment
por: Takemasa, Ichiro, et al.
Publicado: (2022)

Comparison of outcomes between symptomatic and asymptomatic patients with colorectal cancer: a propensity score-matched analysis of surgical invasiveness, medical costs and oncological outcomes
por: Inada, Ryo, et al.
Publicado: (2017)

The Protective Role of Heme Oxygenase-1 in Atherosclerotic Diseases
por: Kishimoto, Yoshimi, et al.
Publicado: (2019)

The Protective Role of Sestrin2 in Atherosclerotic and Cardiac Diseases
por: Kishimoto, Yoshimi, et al.
Publicado: (2021)

Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB
por: Machitani, Mitsuhiro, et al.
Publicado: (2017)

Multidisciplinary oncolytic virotherapy for gastrointestinal cancer
por: Fujiwara, Toshiyoshi
Publicado: (2019)

Direct implantation of hair-follicle-associated pluripotent (HAP) stem cells repairs intracerebral hemorrhage and reduces neuroinflammation in mouse model
por: Obara, Koya, et al.
Publicado: (2023)

Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer
por: Taniguchi, Fumitaka, et al.
Publicado: (2021)

Clinical outcomes of women with ovarian metastases of colorectal cancer treated with oophorectomy with respect to their somatic mutation profiles
por: Mori, Yoshiko, et al.
Publicado: (2018)

Complementarity of ultrasound and fluorescence imaging in an orthotopic mouse model of pancreatic cancer
por: Snyder, Cynthia S, et al.
Publicado: (2009)

BRAF V600E mutation is a predictive indicator of upfront chemotherapy for stage IV colorectal cancer
por: Morikawa, Tatsuya, et al.
Publicado: (2018)

Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model
por: Igarashi, Kentaro, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0vt32uujipln0ks3mtglunq4jn