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Wogonin Has Multiple Anti-Cancer Effects by Regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 Pathways and Inducing Apoptosis in Human Lung Adenocarcinoma Cell Line A549

Wogonin is a plant monoflavonoid which has been reported to inhibit cell growth and/or induce apoptosis in various tumors. The present study examined the apoptosis-inducing activity and underlying mechanism of action of wogonin in A549 cells. The results showed that wogonin was a potent inhibitor of...

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Detalles Bibliográficos
Autores principales: Chen, Xin-mei, Bai, Yang, Zhong, Yu-jian, Xie, Xiao-lin, Long, Han-wu, Yang, Yu-yin, Wu, Shi-gen, Jia, Qiang, Wang, Xiao-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827163/
https://www.ncbi.nlm.nih.gov/pubmed/24265759
http://dx.doi.org/10.1371/journal.pone.0079201