A ΔclpB Mutant of Francisella tularensis Subspecies holarctica Strain, FSC200, Is a More Effective Live Vaccine than F. tularensis LVS in a Mouse Respiratory Challenge Model of Tularemia

Francisella tularensis subsp. tularensis is a highly virulent pathogen for humans especially if inhaled. Consequently, it is considered to be a potential biothreat agent. An experimental vaccine, F. tularensis live vaccine strain, derived from the less virulent subsp. holarctica, was developed more...

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Detalles Bibliográficos
Autores principales: Golovliov, Igor, Twine, Susan M., Shen, Hua, Sjostedt, Anders, Conlan, Wayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827231/
https://www.ncbi.nlm.nih.gov/pubmed/24236032
http://dx.doi.org/10.1371/journal.pone.0078671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827231/
https://www.ncbi.nlm.nih.gov/pubmed/24236032
http://dx.doi.org/10.1371/journal.pone.0078671

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