Osteoblast CFTR Inactivation Reduces Differentiation and Osteoprotegerin Expression in a Mouse Model of Cystic Fibrosis-Related Bone Disease

Low bone mass and increased fracture risk are recognized complications of cystic fibrosis (CF). CF-related bone disease (CFBD) is characterized by uncoupled bone turnover—impaired osteoblastic bone formation and enhanced osteoclastic bone resorption. Intestinal malabsorption, vitamin D deficiency an...

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Detalles Bibliográficos
Autores principales: Stalvey, Michael S., Clines, Katrina L., Havasi, Viktoria, McKibbin, Christopher R., Dunn, Lauren K., Chung, W. Joon, Clines, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827431/
https://www.ncbi.nlm.nih.gov/pubmed/24236172
http://dx.doi.org/10.1371/journal.pone.0080098

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