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Lifelong Obesity in a Polygenic Mouse Model Prevents Age- and Diet-Induced Glucose Intolerance– Obesity Is No Road to Late-Onset Diabetes in Mice

AIMS/HYPOTHESIS: Visceral obesity holds a central position in the concept of the metabolic syndrome characterized by glucose intolerance in humans. However, until now it is unclear if obesity by itself is responsible for the development of glucose intolerance. METHODS: We have used a novel polygenic...

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Detalles Bibliográficos
Autores principales:	Renne, Ulla, Langhammer, Martina, Brenmoehl, Julia, Walz, Christina, Zeissler, Anja, Tuchscherer, Armin, Piechotta, Marion, Wiesner, Rudolf J., Bielohuby, Maximilian, Hoeflich, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827443/ https://www.ncbi.nlm.nih.gov/pubmed/24236159 http://dx.doi.org/10.1371/journal.pone.0079788

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