What Is Inflammatory Breast Cancer? Revisiting the Case Definition

The case definition for inflammatory breast cancer (IBC) is controversial. The American Joint Committee on Cancer defines IBC as redness, warmth and edema involving at least half the breast. The SEER program relies on a pathologic finding of dermal lymphatic invasion and recently added those with cl...

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Detalles Bibliográficos
Autores principales: Levine, Paul H., Zolfaghari, Ladan, Young, Heather, Hafi, Muhannad, Cannon, Timothy, Ganesan, Chitra, Veneroso, Carmela, Brem, Rachel, Sherman, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827596/
https://www.ncbi.nlm.nih.gov/pubmed/24281037
http://dx.doi.org/10.3390/cancers2010143
Descripción
Sumario:The case definition for inflammatory breast cancer (IBC) is controversial. The American Joint Committee on Cancer defines IBC as redness, warmth and edema involving at least half the breast. The SEER program relies on a pathologic finding of dermal lymphatic invasion and recently added those with clinical involvement of more than 3/4 of the breast. We established a registry to collect information and specimens from IBC patients to clarify the epidemiology and biology of these tumors. The goals of this report are to suggest improvements regarding case definitions and provide data on the variety of presentations relevant to early diagnosis.

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