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The impact of Folate Pathway Polymorphisms Combined to Nutritional Deficiency As a Maternal Predisposition Factor for Down Syndrome
Polymorphisms in genes encoding folate metabolizing enzymes have been linked to an increased risk of maternal chromosomal nondisjunction in several populations. With the purpose of evaluating this relationship, we compared the frequencies of 677C>T and 1298A>C polymorphisms in the methylenetet...
Autores principales: | Santos-Rebouças, C. B., Corrêa, J. C., Bonomo, A., Fintelman-Rodrigues, N., Moura, K. C. V., Rodrigues, C. S. C., Santos, J. M., Pimentel, M. M. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827818/ https://www.ncbi.nlm.nih.gov/pubmed/19096127 http://dx.doi.org/10.1155/2008/487023 |
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