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Specialized Dynamical Properties of Promiscuous Residues Revealed by Simulated Conformational Ensembles

[Image: see text] The ability to interact with different partners is one of the most important features in proteins. Proteins that bind a large number of partners (hubs) have been often associated with intrinsic disorder. However, many examples exist of hubs with an ordered structure, and evidence o...

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Detalles Bibliográficos
Autores principales: Fornili, Arianna, Pandini, Alessandro, Lu, Hui-Chun, Fraternali, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827836/
https://www.ncbi.nlm.nih.gov/pubmed/24250278
http://dx.doi.org/10.1021/ct400486p