Cargando…

Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals

BACKGROUND: Although the potential of biomarkers to aid in early detection of colorectal cancer (CRC) is recognized and numerous biomarker candidates have been reported in the literature, to date only few molecular markers have been approved for daily clinical use. METHODS: In order to improve the t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thorsen, Stine Buch, Lundberg, Martin, Villablanca, Andrea, Christensen, Sarah Louise T, Belling, Kirstine Christensen, Nielsen, Birgitte Sander, Knowles, Mick, Gee, Nick, Nielsen, Hans Jørgen, Brünner, Nils, Christensen, Ib Jarle, Fredriksson, Simon, Stenvang, Jan, Assarsson, Erika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827929/ https://www.ncbi.nlm.nih.gov/pubmed/24107468 http://dx.doi.org/10.1186/1479-5876-11-253

Ejemplares similares

Gel-Based Proteomics of Clinical Samples Identifies Potential Serological Biomarkers for Early Detection of Colorectal Cancer
por: Thorsen, Stine F., et al.
Publicado: (2019)

Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study
por: Thorsen, Stine B, et al.
Publicado: (2013)

Early Detection and Recurrence of Colorectal Adenomas by Combination of Eight Cancer-Associated Biomarkers in Plasma
por: Rasmussen, Louise, et al.
Publicado: (2020)

Circulating cell-free nucleosomes as biomarkers for early detection of colorectal cancer
por: Rasmussen, Louise, et al.
Publicado: (2017)

High levels of microRNA-21 in the stroma of colorectal cancers predict short disease-free survival in stage II colon cancer patients
por: Nielsen, Boye Schnack, et al.
Publicado: (2010)

Cathepsin X in serum from patients with colorectal cancer: relation to prognosis
por: Vizin, Tjasa, et al.
Publicado: (2012)

Measuring ERCC1 protein expression in cancer specimens: Validation of a novel antibody
por: Smith, David Hersi, et al.
Publicado: (2014)

Data fusion in metabolomic cancer diagnostics
por: Bro, Rasmus, et al.
Publicado: (2012)

Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients
por: Vižin, Tjaša, et al.
Publicado: (2014)

An explorative analysis of ERCC1-19q13 copy number aberrations in a chemonaive stage III colorectal cancer cohort
por: Smith, David Hersi, et al.
Publicado: (2013)

ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer
por: Palshof, Jesper Andreas, et al.
Publicado: (2020)

Screening for colorectal cancer: possible improvements by risk assessment evaluation?
por: Nielsen, Hans J, et al.
Publicado: (2011)

Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood
por: Lundberg, Martin, et al.
Publicado: (2011)

Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability
por: Assarsson, Erika, et al.
Publicado: (2014)

miRNA profiling of circulating EpCAM(+) extracellular vesicles: promising biomarkers of colorectal cancer
por: Ostenfeld, Marie Stampe, et al.
Publicado: (2016)

Mechanisms of Topoisomerase I (TOP1) Gene Copy Number Increase in a Stage III Colorectal Cancer Patient Cohort
por: Smith, David Hersi, et al.
Publicado: (2013)

Circulating VEGF As a Biological Marker in Patients with Rheumatoid Arthritis? Preanalytical and Biological Variability in Healthy Persons and in Patients
por: Hetland, Merete Lund, et al.
Publicado: (2008)

Urokinase-type plasminogen activator receptor (uPAR) on tumor-associated macrophages is a marker of poor prognosis in colorectal cancer
por: Illemann, Martin, et al.
Publicado: (2014)

Implications of ABCG2 Expression on Irinotecan Treatment of Colorectal Cancer Patients: A Review
por: Nielsen, Dorte Lisbet, et al.
Publicado: (2017)

Flow Cytometric Bivariate Analysis of DNA and Cytokeratin in Colorectal Cancer
por: Post, Carolin, et al.
Publicado: (2002)

Mucosal expression of PI3, ANXA1, and VDR discriminates Crohn’s disease from ulcerative colitis
por: James, Jaslin Pallikkunnath, et al.
Publicado: (2023)

The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells
por: Pedraz-Cuesta, Elena, et al.
Publicado: (2015)

The course of pain hypersensitivity according to painDETECT in patients with rheumatoid arthritis initiating treatment: results from the prospective FRAME-cohort study
por: Rifbjerg-Madsen, Signe, et al.
Publicado: (2018)

Clean Colorectum at Diagnostic Colonoscopy: Subsequent Detection of Extracolonic Malignancies by Plasma Protein Biomarkers?
por: Wilhelmsen, Michael, et al.
Publicado: (2018)

The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer
por: Lin, Xue, et al.
Publicado: (2015)

Identification and validation of potential prognostic and predictive miRNAs of epithelial ovarian cancer
por: Prahm, Kira Philipsen, et al.
Publicado: (2018)

Prognostic factors for relapse in patients with clinical stage I testicular cancer: protocol for a Danish nationwide cohort study
por: Wagner, Thomas, et al.
Publicado: (2019)

Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation study
por: Jensen, Sarah Østrup, et al.
Publicado: (2019)

Mucoadhesive Dendrons Conjugated to Mesoporous Silica Nanoparticles as a Drug Delivery Approach for Orally Administered Biopharmaceuticals
por: Tollemeto, Matteo, et al.
Publicado: (2023)

The predictive ability of indirect genetic models is reduced when culled animals are omitted from the data
por: Ask, Birgitte, et al.
Publicado: (2020)

No effect of 10 weeks erythropoietin treatment on lipid oxidation in healthy men
por: Risikesan, Jeyanthini, et al.
Publicado: (2020)

Systemic Immune Modulation in Gliomas: Prognostic Value of Plasma IL-6, YKL-40, and Genetic Variation in YKL-40
por: Holst, Camilla Bjørnbak, et al.
Publicado: (2020)

MicroRNA characteristics in epithelial ovarian cancer
por: Prahm, Kira Philipsen, et al.
Publicado: (2021)

Olfactory testing in consecutive patients referred with suspected dementia
por: Christensen, Ib Thrane, et al.
Publicado: (2017)

Selection for social genetic effects in purebreds increases growth in crossbreds
por: Ask, Birgitte, et al.
Publicado: (2021)

Selection for social genetic effects in purebred pigs improves behaviour and handling of their crossbred progeny
por: Nielsen, Bjarne, et al.
Publicado: (2023)

Use of Oral Anticoagulation Therapy in Atrial Fibrillation after Stroke: Results from a Nationwide Registry
por: Jespersen, Stine Funder, et al.
Publicado: (2013)

A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol
por: Kümler, Iben, et al.
Publicado: (2015)

Pre- and Perioperative Inflammatory Biomarkers in Older Patients Resected for Localized Colorectal Cancer: Associations with Complications and Prognosis
por: Dolin, Troels Gammeltoft, et al.
Publicado: (2021)

Can the painDETECT Questionnaire score and MRI help predict treatment outcome in rheumatoid arthritis: protocol for the Frederiksberg hospital's Rheumatoid Arthritis, pain assessment and Medical Evaluation (FRAME-cohort) study
por: Rifbjerg-Madsen, Signe, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_o0e34fj4i2atc2fg68pi0kdc4a