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Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging

BACKGROUND: Increasing evidence indicates that neuroinflammation is a critical factor contributing to the progression of various neurodegenerative diseases. The IKK/NF-κB signalling system is a central regulator of inflammation, but it also affects neuronal survival and differentiation. A complex in...

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Detalles Bibliográficos
Autores principales:	Maqbool, Ayesha, Lattke, Michael, Wirth, Thomas, Baumann, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827934/ https://www.ncbi.nlm.nih.gov/pubmed/24119288 http://dx.doi.org/10.1186/1750-1326-8-40

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