Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa

Pharmacometricians are virtually nonexistent in Africa and the developing world. The unrelenting burden of infectious diseases, which are often treated using medicines with narrow effectiveness and safety dose ranges, and the growing prevalence and recognition of non-communicable diseases represent...

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Autores principales: Pillai, G, Davies, G, Denti, P, Steimer, J-L, McIlleron, H, Zvada, S, Chigutsa, E, Ngaimisi, E, Mirza, F, Tadmor, B, Holford, N H G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828009/
https://www.ncbi.nlm.nih.gov/pubmed/23985967
http://dx.doi.org/10.1038/psp.2013.45
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author Pillai, G
Davies, G
Denti, P
Steimer, J-L
McIlleron, H
Zvada, S
Chigutsa, E
Ngaimisi, E
Mirza, F
Tadmor, B
Holford, N H G
author_facet Pillai, G
Davies, G
Denti, P
Steimer, J-L
McIlleron, H
Zvada, S
Chigutsa, E
Ngaimisi, E
Mirza, F
Tadmor, B
Holford, N H G
author_sort Pillai, G
collection PubMed
description Pharmacometricians are virtually nonexistent in Africa and the developing world. The unrelenting burden of infectious diseases, which are often treated using medicines with narrow effectiveness and safety dose ranges, and the growing prevalence and recognition of non-communicable diseases represent significant threats for the patients, although affording an opportunity for advancing science. This article outlines the case for pharmacometricians to redirect their expertise to focus on the disease burden affecting the developing world.
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spelling pubmed-38280092013-11-15 Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa Pillai, G Davies, G Denti, P Steimer, J-L McIlleron, H Zvada, S Chigutsa, E Ngaimisi, E Mirza, F Tadmor, B Holford, N H G CPT Pharmacometrics Syst Pharmacol Perspective Pharmacometricians are virtually nonexistent in Africa and the developing world. The unrelenting burden of infectious diseases, which are often treated using medicines with narrow effectiveness and safety dose ranges, and the growing prevalence and recognition of non-communicable diseases represent significant threats for the patients, although affording an opportunity for advancing science. This article outlines the case for pharmacometricians to redirect their expertise to focus on the disease burden affecting the developing world. Nature Publishing Group 2013-08 2013-08-28 /pmc/articles/PMC3828009/ /pubmed/23985967 http://dx.doi.org/10.1038/psp.2013.45 Text en Copyright © 2013 American Society for Clinical Pharmacology and Therapeutics http://creativecommons.org/licenses/by-nc-nd/3.0/ CPT: Pharmacometrics and Systems Pharmacology is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Perspective
Pillai, G
Davies, G
Denti, P
Steimer, J-L
McIlleron, H
Zvada, S
Chigutsa, E
Ngaimisi, E
Mirza, F
Tadmor, B
Holford, N H G
Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa
title Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa
title_full Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa
title_fullStr Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa
title_full_unstemmed Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa
title_short Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa
title_sort pharmacometrics: opportunity for reducing disease burden in the developing world: the case of africa
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828009/
https://www.ncbi.nlm.nih.gov/pubmed/23985967
http://dx.doi.org/10.1038/psp.2013.45
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