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Conformational Coupling between Receptor and Kinase Binding Sites through a Conserved Salt Bridge in a Signaling Complex Scaffold Protein

Bacterial chemotaxis is one of the best studied signal transduction pathways. CheW is a scaffold protein that mediates the association of the chemoreceptors and the CheA kinase in a ternary signaling complex. The effects of replacing conserved Arg62 of CheW with other residues suggested that the sca...

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Detalles Bibliográficos
Autores principales: Ortega, Davi R., Mo, Guoya, Lee, Kwangwoon, Zhou, Hongjun, Baudry, Jerome, Dahlquist, Frederick W., Zhulin, Igor B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828127/
https://www.ncbi.nlm.nih.gov/pubmed/24244143
http://dx.doi.org/10.1371/journal.pcbi.1003337