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Substrate-Driven Mapping of the Degradome by Comparison of Sequence Logos
Sequence logos are frequently used to illustrate substrate preferences and specificity of proteases. Here, we employed the compiled substrates of the MEROPS database to introduce a novel metric for comparison of protease substrate preferences. The constructed similarity matrix of 62 proteases can be...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828135/ https://www.ncbi.nlm.nih.gov/pubmed/24244149 http://dx.doi.org/10.1371/journal.pcbi.1003353 |