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Resistance of M. leprae to Quinolones: A Question of Relativity?
Multidrug resistant leprosy, defined as resistance to rifampin, dapsone and fluoroquinolones (FQ), has been described in Mycobacterium leprae. However, the in vivo impact of fluoroquinolone resistance, mainly mediated by mutations in DNA gyrase (GyrA(2)GyrB(2)), has not been precisely assessed. Our...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828155/ https://www.ncbi.nlm.nih.gov/pubmed/24244784 http://dx.doi.org/10.1371/journal.pntd.0002559 |