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Resistance of M. leprae to Quinolones: A Question of Relativity?

Multidrug resistant leprosy, defined as resistance to rifampin, dapsone and fluoroquinolones (FQ), has been described in Mycobacterium leprae. However, the in vivo impact of fluoroquinolone resistance, mainly mediated by mutations in DNA gyrase (GyrA(2)GyrB(2)), has not been precisely assessed. Our...

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Detalles Bibliográficos
Autores principales: Veziris, Nicolas, Chauffour, Aurélie, Escolano, Sylvie, Henquet, Sarah, Matsuoka, Masanori, Jarlier, Vincent, Aubry, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828155/
https://www.ncbi.nlm.nih.gov/pubmed/24244784
http://dx.doi.org/10.1371/journal.pntd.0002559

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