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Tumor Cell Expression of Vascular Endothelial Growth Factor Receptor 2 Is an Adverse Prognostic Factor in Patients with Squamous Cell Carcinoma of the Lung
A robust immunohistochemical (IHC) assay for VEGFR2 was developed to investigate its utility for patient tailoring in clinical trials. The sensitivity, specificity, and selectivity of the IHC assay were established by siRNA knockdown, immunoblotting, mass spectrometry, and pre-absorption experiments...
Autores principales: | Holzer, Timothy R., Fulford, Angie D., Nedderman, Drew M., Umberger, Tara S., Hozak, Rebecca R., Joshi, Adarsh, Melemed, Symantha A., Benjamin, Laura E., Plowman, Gregory D., Schade, Andrew E., Ackermann, Bradley L., Konrad, Robert J., Nasir, Aejaz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828187/ https://www.ncbi.nlm.nih.gov/pubmed/24244672 http://dx.doi.org/10.1371/journal.pone.0080292 |
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