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The Ratios of CD8(+) T Cells to CD4(+)CD25(+) FOXP3(+) and FOXP3(-) T Cells Correlate with Poor Clinical Outcome in Human Serous Ovarian Cancer
Ovarian cancer is an immune reactive malignancy with a complex immune suppressive network that blunts successful immune eradication. This suppressive microenvironment may be mediated by recruitment or induction of CD4(+) regulatory T cells (Tregs). Our study sought to investigate the association of...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828213/ https://www.ncbi.nlm.nih.gov/pubmed/24244610 http://dx.doi.org/10.1371/journal.pone.0080063 |