The Ratios of CD8(+) T Cells to CD4(+)CD25(+) FOXP3(+) and FOXP3(-) T Cells Correlate with Poor Clinical Outcome in Human Serous Ovarian Cancer

Ovarian cancer is an immune reactive malignancy with a complex immune suppressive network that blunts successful immune eradication. This suppressive microenvironment may be mediated by recruitment or induction of CD4(+) regulatory T cells (Tregs). Our study sought to investigate the association of...

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Detalles Bibliográficos
Autores principales: Preston, Claudia C., Maurer, Matthew J., Oberg, Ann L., Visscher, Daniel W., Kalli, Kimberly R., Hartmann, Lynn C., Goode, Ellen L., Knutson, Keith L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828213/
https://www.ncbi.nlm.nih.gov/pubmed/24244610
http://dx.doi.org/10.1371/journal.pone.0080063

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