Antinociceptive Effects of Analgesic-Antitumor Peptide (AGAP), a Neurotoxin from the Scorpion Buthus martensii Karsch, on Formalin-Induced Inflammatory Pain through a Mitogen-Activated Protein Kinases–Dependent Mechanism in Mice

In the present study, we investigated the anti-nociceptive effect and the underlying mechanism of the analgesic-antitumor peptide (AGAP), a neurotoxin from the scorpion Buthus martensii Karsch. AGAP in doses of 0.2, 1 and 5 µg was injected intraplantarly (i.pl.) before formalin injection 10 min at t...

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Detalles Bibliográficos
Autores principales: Mao, Qinghong, Ruan, Jiaping, Cai, Xueting, Lu, Wuguang, Ye, Juan, Yang, Jie, Yang, Yang, Sun, Xiaoyan, Cao, Junli, Cao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828337/
https://www.ncbi.nlm.nih.gov/pubmed/24244296
http://dx.doi.org/10.1371/journal.pone.0078239

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