Radiosensitization of noradrenaline transporter-expressing tumour cells by proteasome inhibitors and the role of reactive oxygen species

BACKGROUND: The radiopharmaceutical (131)I-metaiodobenzylguanidine ((131)I-MIBG) is used for the targeted radiotherapy of noradrenaline transporter (NAT)-expressing neuroblastoma. Enhancement of (131)I-MIBG's efficacy is achieved by combination with the topoisomerase I inhibitor topotecan - cur...

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Detalles Bibliográficos
Autores principales: Rae, Colin, Tesson, Mathias, Babich, John W, Boyd, Marie, Mairs, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828419/
https://www.ncbi.nlm.nih.gov/pubmed/24219987
http://dx.doi.org/10.1186/2191-219X-3-73

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828419/
https://www.ncbi.nlm.nih.gov/pubmed/24219987
http://dx.doi.org/10.1186/2191-219X-3-73

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