Cargando…
Radiosensitization of noradrenaline transporter-expressing tumour cells by proteasome inhibitors and the role of reactive oxygen species
BACKGROUND: The radiopharmaceutical (131)I-metaiodobenzylguanidine ((131)I-MIBG) is used for the targeted radiotherapy of noradrenaline transporter (NAT)-expressing neuroblastoma. Enhancement of (131)I-MIBG's efficacy is achieved by combination with the topoisomerase I inhibitor topotecan - cur...
Autores principales: | Rae, Colin, Tesson, Mathias, Babich, John W, Boyd, Marie, Mairs, Robert J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828419/ https://www.ncbi.nlm.nih.gov/pubmed/24219987 http://dx.doi.org/10.1186/2191-219X-3-73 |
Ejemplares similares
-
Differential in radiosensitizing potency of enantiomers of the fatty acid synthase inhibitor C75
por: Rae, Colin, et al.
Publicado: (2016) -
Preliminary evaluation of prostate‐targeted radiotherapy using (131)I‐MIP‐1095 in combination with radiosensitising chemotherapeutic drugs
por: Tesson, Mathias, et al.
Publicado: (2016) -
Intracellular Amplifiers of Reactive Oxygen Species Affecting Mitochondria as Radiosensitizers
por: Xu, Hong-Gui, et al.
Publicado: (2021) -
An evaluation in vitro of the efficacy of nutlin-3 and topotecan in combination with (177)Lu-DOTATATE for the treatment of neuroblastoma
por: Tesson, Mathias, et al.
Publicado: (2018) -
Noradrenaline transporter PET reflects neurotoxin-induced noradrenaline level decrease in the rat hippocampus
por: Sakai, Takayuki, et al.
Publicado: (2023)