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3D chromatin interactions organize Yan chromatin occupancy and repression at the even-skipped locus

Long-range integration of transcriptional inputs is critical for gene expression, yet the mechanisms remain poorly understood. We investigated the molecular determinants that confer fidelity to expression of the heart identity gene even-skipped (eve). Targeted deletion of regions bound by the repres...

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Detalles Bibliográficos
Autores principales: Webber, Jemma L., Zhang, Jie, Mitchell-Dick, Aaron, Rebay, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828515/
https://www.ncbi.nlm.nih.gov/pubmed/24186975
http://dx.doi.org/10.1101/gad.225789.113