Cargando…

Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

More than half of human genes use alternative cleavage and polyadenylation (ApA) to generate mRNA transcripts that differ in the lengths of their 3′ untranslated regions (UTRs), thus altering the post-transcriptional fate of the message and likely the protein output. The extent of 3′ UTR variation a...

Descripción completa

Detalles Bibliográficos
Autores principales: Lianoglou, Steve, Garg, Vidur, Yang, Julie L., Leslie, Christina S., Mayr, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828523/
https://www.ncbi.nlm.nih.gov/pubmed/24145798
http://dx.doi.org/10.1101/gad.229328.113