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Interactions between the discoidin domain receptor 1 and β1 integrin regulate attachment to collagen

Collagen degradation by phagocytosis is essential for physiological collagen turnover and connective tissue homeostasis. The rate limiting step of phagocytosis is the binding of specific adhesion receptors, which include the integrins and discoidin domain receptors (DDR), to fibrillar collagen. Whil...

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Detalles Bibliográficos
Autores principales: Staudinger, Lisa A., Spano, Stephen J., Lee, Wilson, Coelho, Nuno, Rajshankar, Dhaarmini, Bendeck, Michelle P., Moriarty, Tara, McCulloch, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828761/
https://www.ncbi.nlm.nih.gov/pubmed/24244851
http://dx.doi.org/10.1242/bio.20135090