Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish

Hedgehog (Hh) signaling is mediated by the Gli transcription factors and, in the zebrafish, plays an important role in patterning both the neural tube and myotome. Using a null allele of the gli2a gene induced by targeted mutagenesis, we show that Gli2a is completely dispensable in the fish but acts...

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Detalles Bibliográficos
Autores principales: Wang, Xingang, Zhao, Zhonghua, Muller, Julius, Iyu, Audrey, Khng, Alexis Jiaying, Guccione, Ernesto, Ruan, Yijun, Ingham, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828767/
https://www.ncbi.nlm.nih.gov/pubmed/24244857
http://dx.doi.org/10.1242/bio.20136262

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