Hepatic Extracellular Signal–Regulated Kinase 2 Suppresses Endoplasmic Reticulum Stress and Protects From Oxidative Stress and Endothelial Dysfunction

BACKGROUND: Insulin signaling comprises 2 major cascades: the insulin receptor substrate/phosphatidylinositol 3′‐kinase/protein kinase B and Ras/Raf/mitogen‐activated protein kinase/kinase/ERK pathways. While many studies on the tissue‐specific effects of the insulin receptor substrate/phosphatidyli...

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Detalles Bibliográficos
Autores principales: Kujiraoka, Takehiko, Satoh, Yasushi, Ayaori, Makoto, Shiraishi, Yasunaga, Arai‐Nakaya, Yuko, Hakuno, Daihiko, Yada, Hirotaka, Kuwada, Naruo, Endo, Shogo, Isoda, Kikuo, Adachi, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828781/
https://www.ncbi.nlm.nih.gov/pubmed/23954796
http://dx.doi.org/10.1161/JAHA.113.000361

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